Question

From the following diseases which can be traced in a family by pedigree analysis?

• A. Cystic Fibrosis
• B. Asthma
• C. Diabetes
• D. Hypertension

Answer 1

Answer:

A. Cystic Fibrosis

(a) The allele for cystic fibrosis is recessive.

(b) Individuals 1 and 2 are heterozygous, because they are normal but produced an affected child. Individual 4 is homozygous recessive, since the allele is recessive and the individual must have two copies of the allele to be affected.

(c) Individuals 3 and 5 are normal but the information presented is not sufficient to determine whether they are homozygous dominant or heterozygous.