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How many steps of decarboxylation lead to the formation of ketoglutaric acid?

AOne

BThree

CTwo

DSeven

Answer:

C. Two

Read Explanation:

  • Two steps of decarboxylation leads to the formation of ketoglutaric acid.

  • When citric acid is formed in the cycle, it then forms cis-acotinic acid and then isocitric acid.

  • Isocitric acid further forms oxalosuccinic acid which finally forms ketoglutaric acid in the presence of oxalosuccinate decarboxylase enzyme.


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