In 1453, Constantinople, the seat of European learning, fell to the Turks.
Constantinople (modern-day Istanbul) was the capital of the Byzantine Empire.
In 1453, it was captured by the Ottoman Turks, led by Sultan Mehmed II.
This event marked the end of the Byzantine Empire.
The fall of Constantinople led to Greek scholars fleeing to Western Europe, bringing with them classical knowledge, which contributed to the European Renaissance.