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One gene one polypeptide hypothesis was proposed by:

ABeadle and Tatum

BBateson and Punnet

CSanger and Ingram

DCrick and Franklin

Answer:

A. Beadle and Tatum

Read Explanation:

  • The one gene-one enzyme hypothesis was proposed by Beadle and Tatum.

  • It suggests that a single gene produces a single enzyme, which later affects an individual step in a metabolic pathway.

  • Beadle demonstrated that one gene in a fruit fly produces one enzyme which in turn controls a single chemical reaction.

  • In this, each gene acts as a chemical molecule and has a particular function.

  • Beadle and Tatum later confirmed this hypothesis using genetic and biochemical studies of the bread mold Neurospora crassa.

  • Neurospora crassa to prove that in a multistep biochemical pathway, each step is controlled by different enzymes and each of these enzymes is encoded by a specific gene.

  • This is called the one gene-one enzyme hypothesis.


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