Question

The first clinical gene therapy was tested in 1990 in the case of:

• A. Adenosine deaminase deficiency
• B. Cystic fibrosis
• C. Emphysema
• D. Phenylketonuria

Answer 1

Answer:

A. Adenosine deaminase deficiency

• ADA deficiency impairs the development and function of immune cells called lymphocytes.

• Lymphocytes are white blood cells that help the body fight infections.

• As a result, people with ADA deficiency often develop pneumonia, chronic diarrhea, and widespread skin rashes.