Question

The first phase of translation is:

• A. Recognition of DNA molecule
• B. Aminoacylation of RNA
• C. Recognition of aminoacids
• D. Binding of mRNA to ribosome

Answer 1

Answer:

D. Binding of mRNA to ribosome

• Translation begins when the small ribosomal subunit binds to the mRNA molecule. This is followed by the binding of a specific initiator tRNA carrying the first amino acid (usually methionine) to the start codon on the mRNA. This step forms the initiation complex and sets the stage for polypeptide synthesis to proceed. Aminoacylation of tRNA (charging tRNA with amino acids) occurs prior but is technically part of aminoacylation, not the first phase of translation itself. Recognition of DNA and amino acids is part of transcription or amino acid activation, not translation initiation.