Question

The given reaction is called gateway step or link reaction between glycolysis and Krebs cycle. Fill the gaps with most suitable choices. Pyruvate + A + COA _B_ Acetyl CoA + _ _C__ + __D_

• A. A-NAD+, B-Dehydrogenase,C- NADH+H+, D-CO2
• B. A-FAD +, B-Decarboxylase, C-FADH2, D-H20 89
• C. A-FMN, B-Dehydrogenase, C-FMNH2, D-CO2
• D. A-NAD+, B-Dehydrogenase, C-NADH+H+, D-H20

Answer 1

Answer:

A. A-NAD+, B-Dehydrogenase,C- NADH+H+, D-CO2

The link reaction is the first step of aerobic respiration and connects the glycolysis process in the cytoplasm to the Krebs cycle in the mitochondrial matrix. The reaction is catalyzed by the enzyme complex pyruvate dehydrogenase. The reaction is simplified as: Pyruvate + NAD⁺ + CoA → Acetyl-CoA + NADH + CO₂ The link reaction is vital in respiration. The acetyl-CoA that is produced enters the Krebs cycle for further oxidation. The Krebs cycle is the primary source of energy for cells.