Question

The modification of which base gives rise to inosine?

• A. Adenine
• B. Guanine
• C. Uridine
• D. Cytosine

Answer 1

Answer:

A. Adenine

Inosine arises through enzymatic modification of a base present in an otherwise completed tRNA chain. The base from which it is derived is adenine, whose carbon 6 is deaminated to give the 6 – keto group of inosine.