The complete oxidation of one molecule of acetyl CoA produces 12 ATP molecules. This is because:
Glucose undergoes glycolysis to produce two pyruvate molecules
The pyruvate molecules are converted to two acetyl CoA molecules
Each acetyl CoA molecule enters the citric acid cycle, also known as the Krebs cycle
The citric acid cycle produces 3 NADH2 (9 ATP), 1 FADH2 (2 ATP), and 1 GTP (1 ATP)