The mitotic spindle is a structure essential for cell division, which organizes the separation and distribution of chromosomes to daughter cells.
This crucial apparatus comprises protein filaments called microtubules, which attach to the centromeres of the chromosomes via kinetochores and align them at the metaphase plate.
As mitosis progresses, the microtubules shorten, exerting forces that pull sister chromatids in opposite directions until each daughter cell gets its share of chromosomes.
While actin and myosin microfilaments are essential for other cellular processes, they do not make up the spindle.
Centrosomes, with their centrioles, have involvement in organizing the spindle’s microtubules, yet it is possible to form these filaments and fulfill their purpose without them.
Thus, asserting that the entire process depends on centrioles alone is inaccurate.
