Question

Which of the following statements is incorrect with respect to alpha-thalassemia?

• A. Involves the genes HBA1 and HBA2
• B. Inherited in a Mendelian dominant fashion
• C. Connected to the deletion of the 16p chromosome
• D. Result in decreased α-globin production

Answer 1

Answer:

B. Inherited in a Mendelian dominant fashion

Alpha-thalassemia is not inherited in a Mendelian dominant fashion. Instead, it is inherited in a Mendelian recessive fashion. It involves the genes HBA1 and HBA2 and it is also connected to the deletion of the 16p chromosome.