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Which one of the following is an immunosuppressant

AStatins

BCyclopsporin

CStreptokinase

DEnterokinase

Answer:

B. Cyclopsporin

Read Explanation:

An immunosuppressant is a drug that suppresses or reduces the strength of the body's immune system. These medications are primarily used to:

  • Prevent organ rejection after a transplant. The recipient's immune system recognizes the new organ as foreign and would normally attack it. Immunosuppressants weaken this response.

  • Treat autoimmune diseases, such as rheumatoid arthritis, psoriasis, and Crohn's disease, where the immune system mistakenly attacks the body's own tissues.

Cyclosporine works by inhibiting the activity of an enzyme called calcineurin. This enzyme is essential for the activation of T-cells, a type of white blood cell that plays a central role in the immune response. By blocking calcineurin, cyclosporine prevents T-cells from producing the necessary cytokines (like interleukin-2) that would normally lead to their proliferation and activation. The result is a suppressed immune system that is less likely to attack transplanted organs or healthy tissues.


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