Question

താഴെ കൊടുത്തിരിക്കുന്നതിൽ ഏതാണ് HbS ജീൻ ഉല്പാദനവുമായ mRNA കോഡോൺ ?

• A. GAG
• B. CAG
• C. GUG
• D. CAC

Answer 1

Answer:

C. GUG

In sickle cell anemia, the genetic reason for the presence of valine is a point mutation in the beta-globin gene, which causes the substitution of glutamic acid (normally found at the sixth position) with valine, leading to the abnormal hemoglobin that causes red blood cells to sickle under low oxygen conditions.