An autosomal recessive disease caused by point mutation is:
ASickle cell anaemia
BGraves' disease
CHaemophilia
DAddison's disease
Answer:
A. Sickle cell anaemia
Read Explanation:
• Sickle cell anaemia results from a specific point mutation (substitution of adenine for thymine in the beta-globin gene on chromosome 11), causing glutamic acid to be replaced by valine at position 6 of the beta-globin chain. This is inherited in an autosomal recessive pattern, where both alleles must carry the mutation for the disease to manifest.
