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Chromosome structure can be observed best during ____

AAnaphase

BMetaphase

CProphase

DNone of the above

Answer:

C. Prophase

Read Explanation:

  • Prophase is the first stage of mitosis in which the genetic material in a cell begins to condense to form chromosomes.

  • The best time to study chromosome size and shape is metaphase/late prophase as the chromosomes are most condensed in this phase.

  • Cells can also be experimentally arrested at metaphase with mitotic poisons such as colchicine.

  • During anaphase, the chromosome splits at the centromere and move to opposite poles.

  • Hence the chromosome can be observed as sister chromatids in this stage.

  • The chromosomes decondense during telophase of cell cycle and loose their identity as discreet units.


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