Question

In which of the following directions does the polypeptide synthesis proceeds?

• A. From both N-terminus and C-terminus
• B. Either from N-terminus or C-terminus
• C. C-terminus to N-terminus
• D. N-terminus to C-terminus

Answer 1

Answer:

D. N-terminus to C-terminus

• The polypeptide synthesis occurs in the direction from N-terminus to C-terminus.

• After the first amino acid has been brought to the ribosome, the second amino acid attaches to the carboxyl carbon of the first amino acid.

• Thus, the first amino acid has an N-terminal free end, and the last amino acid is a C-terminal free end.