Question

What is the amino acid present in the binding pocket of glutaminyl amino acyl tRNA synthetase?

• A. Asp
• B. Lys
• C. Arg
• D. Gln

Answer 1

Answer:

D. Gln

The 3’-OH of the aminoacyl arm of the tRNA enters the binding pocket of the synthetase to interact with a Gln amino acid correctly placed. This is used to distinguish it from Asp and Asn.