Question

Which of the following disorder is an example of point mutation?

• A. Sickle cell anaemia
• B. Night blindness
• C. Down’s syndrome
• D. Thalassemia

Answer 1

Answer:

A. Sickle cell anaemia

Sickle cell anemia (SCA) is caused by a point mutation in the hemoglobin beta gene (\(HBB\)) on chromosome 11. This mutation replaces the amino acid glutamic acid with valine at position 6 of the beta-globin chain